Kimbrough's body of work reflects a lifetime of performing, writing and collaborating from more angles than Da Vinci's protractor. True to his search for universal truths, his profound musical knowledge and expert creations reflect years of learning the intricacies of folk, blues, gospel, country, rock'n'roll, punk rock and jazz. With songs recorded by Jimmy Buffett, Little Feat, Jack Ingram, Todd Snider and others, Kimbrough's multidisciplinary approach has led to many desirable collaborations in the studio and on-stage with well-known artists, including Rosanne Cash, Guy Clark, Rodney Crowell, Steve Earle, Gomez, Emmylou Harris, the Jayhawks, Mark Knopfler, Buddy Miller, John Prine, Toumani Diabate, Kim Richey, Josh Rouse, Matthew Ryan, Billy Joe Shaver, Todd Snider, Mavis Staples, Garrison Starr, Adrienne Young, and others.

Dubbed an "Alien" performer as a way to explain his masterful performance on the guitar, Kimbrough was recognized in 2004 as the "Instrumentalist of the Year" by the Americana Music Association -- an award that had previously been awarded three years in a row to Dobro ace Jerry Douglas.